What is Colorecatal polyps or colon cancer? A colorectal polyp is a small clump of epithelial cells that form a small bump or overgrowth of tissue along the lining of the colon or rectum. The cells lining the colon and rectum are constantly dividing, and typically when there’s an overgrowth of tissue it’s benign, but some can become malignant, meaning that the dividing cells can start invading nearby tissues over time. Types of Colorectal polyps There are various types of colorectal polyps. The most common ones are adenomatous polyps ,also called colonic adenomas. They form when there is a mutation in the adenomatous polypos is coli gene or APC gene, which is a tumor suppressor gene that regulates cell grow. When the APC gene is mutated, the epithelial cells start to quickly divide forming polyps. But even though they are dividing, these polyps only become malignant - meaning they only invade nearby tissues if there are additional mutations in other tumor suppressor genes like the p53 ...
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